USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P52788 USC-OGP 2-DE database:  P52788 P52788 General information about the entry View entry in simple text format Entry name SPSY_HUMAN Primary accession number P52788 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Spermine synthase; Short=SPMSY; EC=2.5.1.22; AltName: Full=Spermidine aminopropyltransferase;. Gene name Name=SMS Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0091: pI=4.87; Mw=42827 Cross-references UniProtKB/Swiss-Prot P52788; SPSY_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SPSY_HUMAN Primary accession number P52788 Secondary accession number(s) A6NHA7 A6NI34 B2R9M0 O00544 Q9UQS1 Sequence was last modified on  May 30, 2000 (version 2) Annotations were last modified on  March 15, 2017 (version 159) Name and origin of the protein Description RecName: Full=Spermine synthase; Short=SPMSY; EC=2.5.1.22; AltName: Full=Spermidine aminopropyltransferase; Gene name Name=SMS Encoded on Name=SMS Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Mental retardation; Phosphoprotein; Polyamine biosynthesis; Polymorphism; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Z49099; CAA88921.1; -; mRNA EMBL AD001528; AAB61308.1; -; mRNA EMBL AK313834; BAG36567.1; -; mRNA EMBL U53331; AAD08634.1; -; Genomic_DNA EMBL U73023; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471074; EAW98984.1; -; Genomic_DNA EMBL BC009898; AAH09898.1; -; mRNA EMBL BC085621; AAH85621.1; -; mRNA CCDS CCDS14203.1; -. [P52788-1]; . CCDS CCDS59161.1; -. [P52788-2]; . PIR S54160; S54160; . RefSeq NP_001245352.1; NM_001258423.1. [P52788-2]; . RefSeq NP_004586.2; NM_004595.4. [P52788-1]; . UniGene Hs.724874; -; . PDB 3C6K; X-ray; 1.95 A; A/B/C/D=5-366 PDB 3C6M; X-ray; 2.45 A; A/B/C/D=5-366 PDBsum 3C6K; -; . PDBsum 3C6M; -; . ProteinModelPortal P52788; -; . SMR P52788; -; . BioGrid 112495; 44; . IntAct P52788; 17; . MINT MINT-5002620; -; . STRING 9606.ENSP00000385746; -; . BindingDB P52788; -; . ChEMBL CHEMBL4934; -; . DrugBank DB00127; Spermine; . iPTMnet P52788; -; . PhosphoSitePlus P52788; -; . BioMuta SMS; -; . DMDM 8247960; -; . OGP P52788; -; . EPD P52788; -; . MaxQB P52788; -; . PaxDb P52788; -; . PeptideAtlas P52788; -; . PRIDE P52788; -; . DNASU 6611; -; . Ensembl ENST00000379404; ENSP00000368714; ENSG00000102172. [P52788-2]; . Ensembl ENST00000404933; ENSP00000385746; ENSG00000102172. [P52788-1]; . GeneID 6611; -; . KEGG hsa:6611; -; . UCSC uc004dag.5; human. [P52788-1]; . CTD 6611; -; . DisGeNET 6611; -; . GeneCards SMS; -; . GeneReviews SMS; -; . HGNC HGNC:11123; SMS; . HPA HPA029849; -; . HPA HPA029852; -; . MalaCards SMS; -; . MIM 300105; gene; . MIM 309583; phenotype; . neXtProt NX_P52788; -; . OpenTargets ENSG00000102172; -; . Orphanet 3063; X-linked intellectual disability; Snyder type; . PharmGKB PA35972; -; . eggNOG KOG1562; Eukaryota; . eggNOG COG0421; LUCA; . GeneTree ENSGT00870000136506; -; . HOGENOM HOG000007053; -; . HOVERGEN HBG004512; -; . InParanoid P52788; -; . KO K00802; -; . OMA EGRMFDY; -; . OrthoDB EOG091G0BXC; -; . PhylomeDB P52788; -; . TreeFam TF324508; -; . BioCyc MetaCyc:HS02362-MONOMER; -; . BRENDA 2.5.1.22; 2681; . Reactome R-HSA-351202; Metabolism of polyamines; . SABIO-RK P52788; -; . UniPathway UPA00249; UER00315; . EvolutionaryTrace P52788; -; . GeneWiki SMS_(gene); -; . GenomeRNAi 6611; -; . PRO PR:P52788; -; . Proteomes UP000005640; Chromosome X; . Bgee ENSG00000102172; -; . CleanEx HS_SMS; -; . ExpressionAtlas P52788; baseline and differential; . Genevisible P52788; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016768; F:spermine synthase activity; IBA:GO_Central; . GO GO:0006555; P:methionine metabolic process; TAS:ProtInc; . GO GO:0006595; P:polyamine metabolic process; TAS:Reactome; . GO GO:0006597; P:spermine biosynthetic process; IBA:GO_Central; . Gene3D 3.40.50.150; -; 1; . InterPro IPR030374; PABS; . InterPro IPR030373; PABS_CS; . InterPro IPR029063; SAM-dependent_MTases; . InterPro IPR015576; Spermine_synthase_animal; . PANTHER PTHR11558:SF34; PTHR11558:SF34; 1; . SUPFAM SSF53335; SSF53335; 1; . PROSITE PS01330; PABS_1; 1; . PROSITE PS51006; PABS_2; 1; .

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